Wembanyama was 8 for 16 on 3-pointers, additionally setting a profession excessive, as San Antonio gained its second straight.
Jordan Poole had 42 factors for Washington, which misplaced its sixth straight.
At 20 years 314 days, Wembanyama is the fourth-youngest participant to attain 50 factors, trailing solely Brandon Jennings (20/52), LeBron James (20/80) and Devin Booker (20/145).
Wembanyama’s earlier excessive was 49 factors in a 130-126 additional time victory over New York.
Wembanyama made not less than six 3-pointers for the third straight sport.
Devin Vassell had 17 factors in his third sport for the Spurs since coming back from offseason surgical procedure to restore a fractured proper foot.
Wizards: Alexandre Sarr blocked Wembanya’s shot within the second quarter and dunked on his fellow Frenchman within the third quarter. Sarr completed with 12 factors, two rebounds, two assists and a block in 25 minutes.
Spurs: Wembanyama is the eighth participant in franchise historical past to attain 50 factors. David Robinson holds the franchise file with 71 factors in opposition to the Los Angeles Clippers on April 24, 1994.
Caught at 48 factors, Wembanyama made an 18-foot jumper for his forty ninth and fiftieth factors with 8:49 remaining to provide San Antonio a 115-98 lead.
Wembanyama is the primary participant in league historical past with 20 3-pointers and 25 blocks over a six-game span.
The Spurs host Los Angeles Lakers on Friday evening within the last sport of a five-game homestand. The are at Atlanta on Friday evening to shut a five-game journey.